C-REACTIVE PROTEIN AS A CRITERION OF EFFICIENCYTREATMENT OF PATIENTS WITH PURULENTNECROTIC INFECTION SOFT TISSUE USING VACUUM THERAPY

Abstract

Vacuum therapy improves the course of all stages of the wound process by reducing local edema and increasing local blood flow, helps to reduce the level of microbial contamination of wounds, and reduces the size of the affected area. With the use of the technology, exudation in the wound area is reduced, a moist environment is maintained, which is the key to successful healing of a soft tissue defect. When examining data that reflect an assessment of the effectiveness of treatment of necrotizing soft tissue infection, the evidence for an assessment has not been reliably determined. Among biochemical parameters, the dynamics of the C-reactive protein content has not been studied enough; the correlation of the C-reactive protein content when using physical methods of treating chronic wounds is unknown. Taking into account the inconsistency of the data, we determined the dynamics of C-reactive protein in patients with wound infection using a vacuum bandage. C-reactive protein is one of the most pathognomonic markers of acute inflammation. Creactive protein is synthesized mainly in hepatocytes, its synthesis is activated by immune complexes, antigens, bacteria, fungi.