MOLECULAR ASSOCIATION BETWEEN PATHOGENIC PSEUDMONAS AEROGINOSA AND TLR4 GENE POLYMORPHISM IN CYSTIC FIBROSIS PATIENTS

Abstract

The distribution of TLR4 (rs4986790) Polymorphism was detected by ARMS-PCR technique There are three genetic types in this locus; A homozygous wild-type (AA) genotype was shown only A allele at 203 bp of the T-ARMS-PCR product. The homozygous (GG) genotype was shown only as the G allele at 288 bp in the T-ARMS-PCR product, while the heterozygous (AG) genotype was shown as the A and G allele at 203 bp and 288 bp product. T-ARMS-PCR. The aim of study is to determination the pathogensis of pseudomonas aeruginosa. The results of the current study revealed that the percentage of males was 48.0%. And the percentage of females was 52.0% for those infected with cystic fibrosis, and there were no clear significant differences on the infection rate