ALKYLATION OF 2H (ALKYL)-SUBSTITUTED PYRIMIDINONES-4

Authors

  • Nurbaev Kh.I. Samarkand State Medical University

Keywords:

Alkyl, Substituted, Pyrimidine, Pyrimidinone

Abstract

We have studied the alkylation reactions of pyrimidinons-4 with nigher alkyl halides. It was shown that, depending on the methyl iodide and methyl tosylate, the alkylation of pyrimidinones-4 with higher alkyl halides in absolute alcohol proceeds with the formation of a mixture of isomeric N-3 and O-4 alkyl products

References

Kh.I.Nurbaev, K.A.Zakhidov, E.O.Oripov, R.A.Samiev, H.M.Shakhidoyatov. Tautomerism and reactivity of substituted pyrimidines. 5. Synthesis and alkylation of 2-selenoxo-6-methylpyrimidinone-4. //Uzb.khim.journal, 1996 No. 1-2 s96-101.

Kh.I.Nurbaev, E.O.Oripov, Kh.M.Shakhidoyatov. "Scientific support of veterinary well-being of animal husbandry in Uzbekistan".

scientific conference dedicated to the 70th anniversary of the formation of UzNIIV // Abstracts of reports Samarkand, 1996.

Kh.I. Nurboev. Alkylation of polydente anions 2-oxo-, -thioxo-, -selenoxo-, -methyl-, -thio-, -amino-6-methyl-, 2-thioxo-6-phenylpyrimidinones-4, with C4-C9 alkyl halides. dis…cond.chem.sci. Tashkent, 1998.

K.A.Zakhidov, E.O.Oripov, Kh.M.Shakhidoyatov. Synthesis of new selenium-containing heterocycles. // All-Union Conf. carbonyl compounds in the synthesis of heterocycles. theses.reports Saratov, 1992. p77.

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Published

2022-11-04

How to Cite

Nurbaev Kh.I. (2022). ALKYLATION OF 2H (ALKYL)-SUBSTITUTED PYRIMIDINONES-4. European Scholar Journal, 3(11), 6-8. Retrieved from https://scholarzest.com/index.php/esj/article/view/2868

Issue

Vol. 3 No. 11 (2022): ESJ

Section

Articles

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