PATHOMORPHOLOGICAL CHARACTERISTICS OF THE INTERNAL ORGANS OF RABBITS UNDER THE INFLUENCE OF ALPHA-SHAKTI

Abstract

This study investigated the toxic effects of the synthetic pyrethroid insecticide Alpha-Shakti using morphological methods. A total of 9 rabbits were divided into three groups. The first group received a single oral dose of 53.57 mg/kg of Alpha-Shakti via a probe. The second group received 89.29 mg/kg in the same manner. The third group served as the control and did not receive the insecticide. After 14 days, the animals were euthanized, and their internal organs were examined histologically. The results showed that the 53.57 mg/kg dose did not cause visible toxic effects. However, the 89.29 mg/kg dose led to vascular disturbances, dystrophic and necrobiotic changes in the myocardium, liver, and kidneys.