THE EFFECT OF CIGARETTE SMOKING ON THE FUNCTIONS OF THE LIVER, KIDNEYS, AND BLOOD ELECTROLYTES
Keywords:
Smoking, Renal Function Test, Liver Function TestAbstract
Cigarette smoking is associated with a variety of disorders via effecting various processes, factors, and mechanisms. This study aimed to inspect the differences in renal function tests, liver enzymes, and serum electrolytes among smokers and non-smokers in Iraqi males. In this study, 75 specimens were collected, during the period between January to March 2024, from Males who attended the private clinical laboratory at Al-Anbar province, Iraq. There was slightly increased in blood urea level among smokers (27.51±9.78 mg/dl) compared to the non-smokers (23.82±5.23 years), but it was not significantly, with a p-value of 0.08>0.05. While serum creatinine was significantly increased among smokers (0.73±0.24 mg/dl) compared to the nonsmokers (0.63±0.13 years), with a p-value of 0.05. When comparing smokers to non-smokers, the levels of both AST and ALT are higher in smokers. Regarding electrolytes, there was not significant increase in potassium (K), and not significant decrease in Chloride (Cl), sodium (Na), magnesium (Mg) levels among smokers compared to non-smokers.
References
H. Jandikova et al., ‘The steroid spectrum during and after quitting smoking’, Physiol Res, vol. 64, p. S211, 2015.
R. Talhout, T. Schulz, E. Florek, J. van Benthem, P. Wester, and A. Opperhuizen, ‘Hazardous Compounds in Tobacco
Smoke’, Int J Environ Res Public Health, vol. 8, no. 2, pp. 613–628, Feb. 2011, doi: 10.3390/ijerph8020613.
S. S. Thomas, L. Zhang, and W. E. Mitch, ‘Molecular mechanisms of insulin resistance in chronic kidney disease’,
Kidney Int, vol. 88, no. 6, pp. 1233–1239, Dec. 2015, doi: 10.1038/KI.2015.305.
S. Soisungwan and M. M. R, ‘Adverse Health Effects of Chronic Exposure to Low-Level Cadmium in Foodstuffs and
Cigarette Smoke’, Environ Health Perspect, vol. 112, no. 10, pp. 1099–1103, Jul. 2004, doi: 10.1289/ehp.6751.
F. Pessione et al., ‘Cigarette smoking and hepatic lesions in patients with chronic hepatitis C’, Hepatology, vol. 34,
no. 1, pp. 121–125, 2001.
E. O. Erdemir and A. Erdemir, ‘The Detection of Salivary Minerals in Smokers and Non-Smokers with Chronic
Periodontitis by the Inductively Coupled Plasma-Atomic Emission Spectrophotometry Technique’, J Periodontol,
vol. 77, no. 6, pp. 990–995, Jun. 2006, doi: https://doi.org/10.1902/jop.2006.050202.
E. J. Sampson, M. A. Baird, C. A. Burtis, E. M. Smith, D. L. Witte, and D. D. Bayse, ‘A coupled-enzyme equilibrium
method for measuring urea in serum: optimization and evaluation of the AACC study group on urea candidate
reference method.’, Clin Chem, vol. 26, no. 7, pp. 816–826, 1980.
D. L. Fabiny and G. Ertingshausen, ‘Automated Reaction-Rate Method for Determination of Serum Creatinine with
the CentrifiChem’, Clin Chem, vol. 17, no. 8, pp. 696–700, Aug. 1971, doi: 10.1093/CLINCHEM/17.8.696.
H. Arazi, B. Taati, F. Rafati Sajedi, and K. Suzuki, ‘Salivary antioxidants status following progressive aerobic
exercise: What are the differences between waterpipe smokers and non-smokers?’, Antioxidants, vol. 8, no. 10, p.
, 2019.
A. Mimran, J. Ribstein, G. DuCailar, and J.-M. Halimi, ‘Albuminuria in normals and essential hypertension’, J
Diabetes Complications, vol. 8, no. 3, pp. 150–156, 1994, doi: https://doi.org/10.1016/1056-8727(94)90032-9.
E. A. Jaimes, R.-X. Tian, and L. Raij, ‘Nicotine: the link between cigarette smoking and the progression of renal
injury?’, American Journal of Physiology-Heart and Circulatory Physiology, vol. 292, no. 1, pp. H76–H82, Jan. 2007,
doi: 10.1152/ajpheart.00693.2006.
K. S. Alsalhen, R. D. Abdalsalam, and A. Abdalsalam, ‘Effect of cigarette smoking on liver functions: a comparative
study conducted among smokers and
H.-J. Aubin, H. Rollema, T. H. Svensson, and G. Winterer, ‘Smoking, quitting, and psychiatric disease: A review’,
Neurosci Biobehav Rev, vol. 36, no. 1, pp. 271–284, 2012, doi: https://doi.org/10.1016/j.neubiorev.2011.06.007.
W. Al-harbi, ‘Electrolytes changes in cigarette smoking male students’, Pakistan Journal of Pharmacology, vol. 29,
no. 1, pp. 33–38, 2012.
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