THE ROLE OF COLLAGEN FIBERS IN WOUND REPAIR PROCESS (SUBJECT REVIEW)

Abstract

Collagen defines as most abundant protein in animals' extracellular matrix. There are approximately 27 distinct forms of collagen that have been identified and defined. CF are the most basic structural elements of the extracellular matrix (ECM) in vertebrates, and they serve to: (1) the energy that called store elastic through muscle tissue deformation, (2) transmits energy preserved into the movement of joint, and (3) transport excess energy from the joint back to the appended muscles for dissipation. Collagen, a fundamental constituent of extracellular matrix, plays an important function in wound healing regulation, whether in its native fibrillar form or as soluble constituents in wound environment. As a result, the importance of collagen structure, kinds, and roles in the wound healing process were examined in this study