THE INCIDENCE OF MYOCARDIAL INFARCTION IN YOUNG PEOPLE

Abstract

Due to the unfavorable tendency towards the "rejuvenation" of ischemic heart disease (IHD), the etiological aspects of the development of acute myocardial infarction (AMI) in 211 patients under the age of 45 have been studied. A retrospective analysis of 132 case histories of patients with an assessment of the epidemiological components of coronary artery disease was carried out. Among the patients, men prevailed (88%), among the risk factors for coronary artery disease, atherogenic dyslipidemia was observed in 100% of cases, 75% of patients smoked, arterial hypertension was noted in 68% of patients, hypodynamia - in 56%, body mass index above normal - in 55%. A burdened family history of coronary artery disease was observed in 42% of patients. According to coronary angiography, 98.8% of patients had stenosis of the coronary arteries over 50%, while 65.0% of them had multivessel disease. There was a statistically significant relationship F = 10.339, (p = 0.002) between the burdened hereditary history and the development of AMI in young patients. Molecular genetic research revealed prothrombotic polymorphisms in the genes of the hemostasis system in 67% of patients.