SCN1A AND CASR ASSOCIATED TO INHERITED EPILEPSY IN BABYLON PROVINCE –IRAQ

Authors

Zahraa M. Al-Taee Department of Biology, College of Science, University of Babylon, Al-Hillah City, Babel Iraq
Ali Hmood Al-Saadi Department of Biology, College of Science, University of Babylon, Al-Hillah City, Babel Iraq
Adnan H. Aljothery Department of Pediatrics, Hammurabi College of Medicine, University of Babylon, Hillah, Iraq

Keywords:

Epilepsy, pediatrics, Scn1a

Abstract

SCN1A mutations are the most common Voltage Gated Sodium Channel mutations in epilepsy, with approximately 1,250 harmful variations causing a variety of epilepsies. SCN1A mutations are, in fact, the most implicated of all epilepsy genes. The parathyroid gland was the first to identify the calcium sensing receptor (CaSR), and it has been shown to play a crucial role in maintaining systemic calcium homeostasis by controlling the production of parathyroid hormone (PTH). Researchers have also looked at the receptor in cells and tissues that aren't directly involved in calcium homeostasis, such as the nervous system (NS), where it plays crucial roles in early neural development for the differentiation of neurons and glial cells, as well as synaptic transmission and plasticity in the adult nervous system

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Published

2023-08-20

How to Cite

Zahraa M. Al-Taee, Ali Hmood Al-Saadi, & Adnan H. Aljothery. (2023). SCN1A AND CASR ASSOCIATED TO INHERITED EPILEPSY IN BABYLON PROVINCE –IRAQ. European Journal of Research Development and Sustainability, 4(8), 20-32. Retrieved from https://scholarzest.com/index.php/ejrds/article/view/3795